Gestational Diabetes Drug used in Pregnancy May Raise Babies’ Risk for Complications

A study published March 30 in JAMA Pediatrics links the use of glyburide in mothers with Gestational Diabetes Mellitus (GDM) to more infant complications including increased visits to the intensive care unit and respiratory distress.   Glyburide (DiaBeta) is an oral tablet that patients prefer over injections of insulin to control blood sugar levels in gestational diabetes.  During the last ten years there has been increasing use of glyburide (DiaBeta) in mothers with gestational diabetes.

The research was conducted using a nationwide, employer-based insurance database.  Data was collected on more than 110,000